Piezoelectric, or piezo, pickups represent another class of pickup. These employ piezoelectricity to generate the musical signal and are popular in hybrid electro-acoustic guitars. A crystal is located under each string, usually in the saddle. When the string vibrates, the shape of the crystal is distorted, and the stresses associated with this change produce tiny voltages across the crystal that can be amplified and manipulated.

Unlike many string instruments which use a bow to create a sound, guitars are played by plucking or strumming the strings on the instrument, which vibrate to create a sound. Chords are played when the guitarist holds their fingers down on more than one individual string to change its length, which in turn changes the frequency of the vibration created - in other words, it creates a different note. Performers often use guitar tabs, rather than sheet music, when learning music: this acts as a kind of 'map' to teach guitarists where to put their fingers on the strings.